1H-Pyrazole-3-carboxylicacid 5-methyl-(CAS# 696-22-0)
| Alamomin haɗari | Xi - Haushi |
| Lambobin haɗari | R36 / 37/38 - Haushi ga idanu, tsarin numfashi da fata. |
| Bayanin Tsaro | S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita. S37/39 - Sanya safofin hannu masu dacewa da kariya / ido |
Gabatarwa
Abu ne na halitta tare da dabarar sinadarai C5H5N2O2. Yawanci mara launi zuwa kodadde rawaya crystalline m.
Filin yana da ƙungiyoyi masu aiki guda biyu, ɗayan zoben pyrazole ne ɗayan kuma ƙungiyar aiki ce ta carboxylic acid. Yana da matsakaicin narkewa kuma yana narkewa cikin ruwa da sauran kaushi na kwayoyin halitta. Ƙungiyar methyl a cikin tsarinta ya sa ya zama hydrophobic.
A matsayin fili na heterocyclic, 5-methyl-yana da nau'ikan ayyukan nazarin halittu. Ana amfani dashi ko'ina a cikin binciken magunguna da haɗin magunguna, sau da yawa azaman albarkatun ƙasa ko matsakaici. Aikace-aikace na musamman sun haɗa da haɗin analogs na bitamin B1, maganin kwari, masu hana plavix (wani fili da ake amfani da shi don hana ci gaban shuka), da makamantansu.
Shiri, 5-methyl-ana iya samun ta hanyar amsawa da zarra na nitrogen na zoben pyrazole tare da wakili na methylating (misali methyl iodide). Ana aiwatar da wannan hanyar ta hanyar amsawar N-methylation, hanyar gama gari ita ce amsawar nucleophile mai dacewa tare da reagent N-methyl.
