2 4-Dichloro-5-methylpyrimidine (CAS# 1780-31-0)
Hadari da Tsaro
| Alamomin haɗari | C - Mai lalacewa |
| Lambobin haɗari | 34- Yana haifar da kuna |
| Bayanin Tsaro | S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita. S36 / 37/39 - Sanya tufafin kariya masu dacewa, safar hannu da kariya / ido / fuska. S45 - Idan akwai haɗari ko kuma idan kun ji rashin lafiya, nemi shawarar likita nan da nan (nuna alamar a duk lokacin da zai yiwu.) S27 – Cire duk gurbatattun tufafi nan da nan. |
| ID na UN | UN 3261 8/PG 2 |
| WGK Jamus | 3 |
| Farashin TSCA | Ee |
| HS Code | 29335990 |
| Matsayin Hazard | 8 |
| Rukunin tattarawa | III |
2 4-Dichloro-5-methylpyrimidine (CAS# 1780-31-0) Bayani
| Amfani | 2, 4-dichloro-5-methylpyrimidine za a iya amfani dashi a cikin shirye-shiryen 2-fluoro-5-trifluoromethylpyrimidine. 2-fluoro-5-trifluoromethylpyrimidine yana da mahimmancin tsaka-tsaki don haɗin magunguna, wanda za'a iya amfani dashi don haɗa nau'in dihydrofuran da aka haɗa, kuma ana iya amfani da mahadi na dihydrofuran zobe azaman G sunadaran GPR119 masu daidaitawa, don maganin ciwon sukari, kiba da cutar dyslipidemia. Bugu da ƙari, 2-fluoro-5-trifluoromethylpyrimidine kuma za a iya amfani da shi azaman tsaka-tsaki a cikin haɗin magunguna don maganin cutar Alzheimer da schizophrenia. |
| shiri | 5-methyluracil 75g (0.59mol), phosphorus oxychloride 236g, triethylamine hydrochloride 16.5g (0.12mol), kara zuwa dauki flask, mai tsanani zuwa 100 ℃ ~ 110 ℃, Reflux dauki 5H, sanyaya zuwa 424 chloride chloride. 1.19mol), zafi amsawar adanawa 2H. Bayan kammala aikin, an dawo da phosphorus oxychloride ta hanyar distillation a ƙarƙashin rage matsa lamba, kuma an ci gaba da distillation a ƙarƙashin matsa lamba don samun 88g (0.54mol) na 2, 4-dichloro-5-methylpyrimidine a cikin yawan amfanin ƙasa na 91.5%. |
Ku rubuta sakonku anan ku aiko mana
