2-Amino-3-bromo-5- (trifluoromethyl) -pyridine (CAS # 79456-30-7)

Gabatarwa

2-Amino-3-brom-5- (trifluoromethyl) pyridine wani nau'in halitta ne tare da tsarin sinadaran C6H4BrF3N2. Tsarin kwayoyin halittarsa ​​ya ƙunshi zoben pyridine da atom ɗin bromine, da kuma ƙungiyar amino da ƙungiyar trifluoromethyl.

Siffofinsa na zahiri sune kamar haka:

Bayyanar: Fari mai ƙarfi

Matsayin narkewa: 82-84 ° C

Tushen tafasa: 238-240 ° C

Girma: 1.86g/cm³

Solubility: Dan kadan mai narkewa a cikin ruwa, mai narkewa a cikin kaushi na halitta kamar ethanol, ether da dichloromethane.

Ɗaya daga cikin manyan amfani da 2-Amino-3-bromo-5- (trifluoromethyl) pyridine shine matsakaicin magunguna. Ana iya amfani da shi don shirya mahadi masu aiki na halitta, kamar kwayoyi, magungunan kashe qwari da rini. Bugu da ƙari, ana iya amfani da ita azaman ligand don shiga cikin halayen sinadarai da ions na ƙarfe ke haifar da su, kamar halayen da aka kayyade na ƙarfe da fahimtar sinadarai.

Ana iya samun hanyar haɗin ginin ta hanyar bromopyridine da amination dauki. Takamaiman matakan sun haɗa da amsawar bromopyridine tare da ammonia, maye gurbin atom ɗin bromine tare da rukunin amino a ƙarƙashin yanayi na asali, sannan gabatar da ƙungiyar trifluoromethyl ƙarƙashin aikin reagent na trifluoromethylation.

Game da bayanin aminci, 2-Amino-3-bromo-5- (trifluoromethyl) pyridine wani fili ne kuma ya kamata a yi amfani da shi tare da kulawa da matakan kariya. Yana iya samun tasiri mai ban haushi da lalata akan idanu, fata da tsarin numfashi. Guji tuntuɓar kai tsaye yayin aiki kuma tabbatar da kyakkyawan yanayin samun iska. Ana ba da shawarar sanya kayan kariya na sirri kamar gilashin kariya, safar hannu da abin rufe fuska yayin amfani. A lokacin zubarwa, da fatan za a bi buƙatun zubar da sinadarai na gida. A lokacin ajiya, ya kamata a adana shi a cikin ƙananan zafin jiki, bushe da wuri mai iska, guje wa hulɗa da oxidants da acid.