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2-Amino-6-bromopyridine (CAS# 19798-81-3) Hoton da aka Fito
  • 2-Amino-6-bromopyridine (CAS# 19798-81-3) 1

2-Amino-6-bromopyridine (CAS# 19798-81-3)

Abubuwan Sinadarai:

Tsarin kwayoyin halitta C5H5BrN2
Molar Mass 173.01
Yawan yawa 1.710± 0.06 g/cm3 (An annabta)
Matsayin narkewa 88-91 ° C (lit.)
Matsayin Boling 273.0 ± 20.0 °C (An annabta)
Wurin Flash 118.9°C
Ruwan Solubility Dan kadan mai narkewa cikin ruwa.
Solubility Chloroform (Dan kadan), methanol (Dan kadan)
Tashin Turi 0.0059mmHg a 25°C
Bayyanar Fari zuwa launin ruwan kasa foda
Launi Dan rawaya zuwa launin ruwan kasa mai haske
pKa 2.73± 0.24 (An annabta)
Yanayin Ajiya Ajiye a cikin duhu wuri, Rufe a bushe, Zazzabin ɗaki

Cikakken Bayani

Tags samfurin

Hadari da Tsaro

Lambobin haɗari R36 / 37/38 - Haushi ga idanu, tsarin numfashi da fata.
R20/21/22 - Cutarwa ta hanyar shakarwa, a cikin hulɗa da fata kuma idan an haɗiye shi.
Bayanin Tsaro S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita.
S36 - Sanya tufafin kariya masu dacewa.
S36 / 37/39 - Sanya tufafin kariya masu dacewa, safar hannu da kariya / ido / fuska.
WGK Jamus 3
HS Code 2933399
Matsayin Hazard HAUSHI

 

 

2-Amino-6-bromopyridine (CAS# 19798-81-3) Bayani

Dubawa 2-amino maye gurbin nitrogen mai dauke da mambobi shida heterocyclic mahadi suna da aikace-aikace masu mahimmanci a cikin masana'antar sinadarai, kamar 2-amino -6-Bromopyridine yana ɗaya daga cikin mahimman tsarin a cikin magungunan roba da ƙwayoyin sinadarai na aikin gona, kuma ana amfani dashi sosai a cikin haɗin gwiwa. na samfuran halitta, magunguna, kayan haske da wasu sinadarai masu kyau.
Aikace-aikace 2-amino da aka maye gurbin nitrogen mai ɗauke da ƙwayoyin heterocyclic guda shida membed suna da mahimman aikace-aikace a cikin masana'antar sinadarai, kamar 2-amino -6-Bromopyridine yana ɗaya daga cikin mahimman tsarin a cikin magungunan roba da ƙwayoyin sinadarai na aikin gona, kuma ana amfani dashi sosai a cikin haɗin gwiwa. na samfuran halitta, magunguna, kayan haske da wasu sinadarai masu kyau.
Shiri Shirye-shiryen 2-amino-6-bromopyridine: Ƙara 2-fluoro-6-bromo-pyridine (1mmol), pentamidine hydrochloride (2mmol), sodium tert-butoxide (3mmol), HO (0.5mL) da diethylene glycol dimethyl ether (2.5). mL) a cikin bututu dauki 25 ml. A dauki da aka za'ayi a 150 ℃ for 24 hours. Bayan an gama amsawa, an sanyaya shi zuwa zafin jiki. Ƙara 10mL na ethyl acetate don quench the reaction, ƙara 6mL na cikakken ruwan gishiri don wankewa, raba tsarin kwayoyin halitta, sa'an nan kuma cire lokaci mai ruwa tare da ethyl acetate na sau 3 (matsayin ethyl acetate kowane lokaci shine 6mL) kuma hada kwayoyin halitta. lokaci, ƙara anhydrous sodium sulfate zuwa bushe, cire sauran ƙarfi ciki har da Organic kaushi da inorganic sauran ƙarfi ta injin distillation, da kuma sa'an nan kuma raba kwayoyin kaushi ta hanyar chromatography shafi don samun samfurin da aka yi niyya 2-amino-6-bromopyridine tare da yawan amfanin ƙasa na 93%.
amfani matsakaicin magunguna.
don ingantaccen haɓakar 7-azafindole a cikin tukunya ɗaya; domin hada magungunan anti-HIV

 

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