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samfur

2,4,5-Trifluorophenylacetic Acid (CAS# 209995-38-0)

Abubuwan Sinadarai:

Tsarin kwayoyin halitta C8H5F3O2

Molar Mass 190.12

Maɗaukaki 1.468± 0.06 g/cm3(an annabta)

Wurin narkewa 121-125 ° C

Boling Point 255.0 ± 35.0 °C (An annabta)

Wurin Flash 108°C

Solubility Chloroform (Dan kadan), DMSO (Dan kadan), Methanol (Dan kadan)

Tashin tururi 0.00866mmHg a 25°C


Cikakken Bayani

Tags samfurin

Aikace-aikace

2,4, 5-trifluorophenylacetic acid fari ne mai ƙarfi da ake amfani dashi don haɗa sabbin sitagliptin tsaka-tsakin magani don kula da nau'in ciwon sukari na II. sitagliptin shine farkon mai hana DPP-IV wanda Merck ya jera. Yana da sakamako mai kyau na warkewa, ƙananan sakamako masu illa, kyakkyawan aminci da haƙuri a cikin jiyya na nau'in ciwon sukari na II, kuma yana da fa'idodin kasuwa.

Ƙayyadaddun bayanai

Bayyanar Crystallization
Launi Fari zuwa Kashe-Fara
pKa 3.78± 0.10 (An annabta)
Yanayin Ajiya An rufe shi a bushe, Zazzabin ɗaki
Bayanin Refractive 1.488

Tsaro

Alamomin haɗari Xi - Haushi
Haushi
Lambobin haɗari R37/38 - Haushi ga tsarin numfashi da fata.
R41 - Hadarin mummunan lalacewa ga idanu
Bayanin Tsaro S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita.
S39 - Sa ido/kariyar fuska.
WGK Jamus 3
Farashin 29163990
Ajin Hazari MAI GIRMA

Shiryawa & Ajiya

Kunshe a cikin ganguna 25kg/50kg. Ajiye a cikin duhu wuri, Rufe a bushe, Zazzabin ɗaki

Gabatarwa

Gabatar da 2,4,5-Trifluorophenylacetic Acid, wani fari mai ƙarfi wanda aka yi amfani da shi sosai a cikin masana'antar harhada magunguna don haɗa tsaka-tsakin sitagliptin don kula da nau'in ciwon sukari na II.

A matsayin muhimmin sashi a cikin samar da sitagliptin, 2,4,5-Trifluorophenylacetic Acid ya taka muhimmiyar rawa wajen haɓaka wannan magani mai inganci. Sitagliptin shine sabon mai hana DPP-IV wanda Merck ya jera kwanan nan. Yana alfahari da kyakkyawan sakamako na warkewa, ƙarancin sakamako masu illa, aminci da haƙuri, kuma ya zama je-zuwa magani a cikin jiyya na nau'in ciwon sukari na II.

Ɗaya daga cikin mahimman fa'idodin 2,4,5-Trifluorophenylacetic Acid shine yana ba da damar samar da sitagliptin akan ƙaramin farashi, yana bawa mutane da yawa damar samun damar yin amfani da wannan magani mai canza rayuwa. Bugu da ƙari, yana da tasiri sosai a maganin ciwon sukari kuma yana ba da sabon bege ga waɗanda ke kokawa da yanayin.

Bayyanar 2,4,5-Trifluorophenylacetic Acid shine farin crystalline fari zuwa kashe-fari foda, yana sauƙaƙa ganowa, rikewa, da jigilar kaya. Hakanan yana da kwanciyar hankali a ƙarƙashin yanayin al'ada, wanda ke nufin cewa ana iya adana shi na dogon lokaci ba tare da lalata ba.

2,4,5-Trifluorophenylacetic acid yana da yawa sosai kuma ana iya amfani dashi a cikin hadaddun wasu hadaddun mahadi da suka wuce tsaka-tsakin sitagliptin. Yana da aikace-aikacen masana'antu daban-daban, gami da samar da agrochemicals, resins, da tsaka-tsaki. Hakanan za'a iya amfani dashi azaman kayan farawa don haɗa nau'ikan ƙwayoyin cuta masu yawa tare da aikace-aikace daban-daban.

A kamfaninmu, muna alfaharin kanmu akan samar da 2,4,5-Trifluorophenylacetic acid mai inganci ga abokan cinikinmu. Samfurin mu ya sadu da ma'auni mafi inganci kuma an ƙera shi yana bin ƙaƙƙarfan jagorori don tabbatar da daidaito da tsabta.

A ƙarshe, 2,4,5-Trifluorophenylacetic Acid sinadari ne mai fa'ida sosai wanda ya zama muhimmin sashi a cikin samar da sitagliptin, magani na farko don nau'in ciwon sukari na II. Ƙwararrensa da tasiri ya sa ya zama kadara mai mahimmanci a cikin masana'antun harhada magunguna da sinadarai, kuma muna alfaharin bayar da ingancin 2,4,5-Trifluorophenylacetic acid ga abokan cinikinmu.


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