3,4-Difluoronitrobenzene (CAS# 369-34-6)
Aikace-aikace
Ana amfani da shi azaman magunguna, tsaka-tsakin magungunan kashe qwari.
Ƙayyadaddun bayanai
Bayyanar Ruwa.
Takamaiman Nauyi 1.437.
Launi Bayyanar rawaya.
Farashin 1944996.
Yanayin Ajiya An rufe shi a bushe, Zazzabin ɗaki.
Kwanciyar hankali. Mai ƙonewa. Rashin jituwa tare da ma'aikatan oxidizing masu ƙarfi, tushe mai ƙarfi.
Fihirisar Refractive n20/D 1.509(lit.).
Yawan Abubuwan Halin Jiki da Chemical 1.441.
wurin tafasa 80-81 ° C (14 mmHg).
Ƙididdigar refractive 1.508-1.51.
zafin jiki 80 ° C.
ruwa mai narkewa marar narkewa.
Tsaro
Lambobin haɗari R36/37/38 - Haɗa kai ga idanu, tsarin numfashi da fata.
R20/21/22 - Cutarwa ta hanyar shakarwa, a cikin hulɗa da fata kuma idan an haɗiye shi.
Bayanin Tsaro S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita.
S36/37/39 - Sanya tufafin kariya masu dacewa, safar hannu da kariya ta ido/ fuska.
S36 - Sanya tufafin kariya masu dacewa.
Bayanan Bayani na UN2810.
WGK Jamus 3.
Saukewa: CZ5710000.
Farashin 29049090.
Hazard Note Irritant.
Matsayin Hazard 6.1.
Rukunin tattarawa na III.
Shiryawa & Ajiya
Kunshe a cikin ganguna 25kg/50kg. Yanayin Ajiya An rufe shi a bushe, Zazzabin ɗaki.
Gabatarwa
3,4-Difluoronitrobenzene: Wani Abu mai Mahimmanci don Masana'antar Magunguna
3,4-Difluoronitrobenzene wani abu ne mai mahimmanci na kwayoyin halitta wanda aka saba amfani dashi azaman mai ƙima ko tsaka-tsaki a cikin samar da magunguna. Wannan sinadari mai amfani kuma ana kiransa da fluoroaromatic, wanda ke nufin cewa ya ƙunshi duka nau'ikan fluorine da ƙungiyoyin aikin ƙanshi. Abubuwan da ake kira fluoroaromatic suna da mahimmancin ginin gine-gine don kera magunguna, magungunan kashe qwari, da sauran sinadarai.
Ɗaya daga cikin mahimman aikace-aikace na 3,4-difluoronitrobenzene shine a matsayin mai aiki na magunguna (API) a cikin samar da magunguna daban-daban. Ana amfani da wannan fili wajen hada magunguna da dama, ciki har da magungunan fungal, maganin rigakafi, magungunan ciwon daji, da magungunan ƙwayoyin cuta. Abubuwan da ke maye gurbin fluoro suna yin wannan fili mai amfani musamman don ƙirƙira magunguna waɗanda za su iya kai hari ga takamaiman cututtukan da ke haifar da ƙwayoyin cuta ko matakai yadda ya kamata.
3,4-Difluoronitrobenzene yana da wasu kaddarorin da suka sa ya zama abin sha'awa don masana'antar magunguna. Misali, fili yana da kyawawan kaddarorin solubility, wanda ke ba shi damar narkewa cikin sauƙi a cikin kewayon kaushi da masu amsawa. Hakanan yana da kwanciyar hankali mai kyau na thermal, ma'ana yana iya jure yanayin zafi da matsi yayin halayen sinadaran. Bugu da ƙari, wannan fili yana da sauƙin haɗawa da keɓewa, wanda ya sa ya zama kayan aiki mai tsada don haɓaka magunguna.
Bayyanar 3,4-difluoronitrobenzene shine ruwa mai tsabta mai launin rawaya, wanda ya sa ya zama sauƙi don ɗauka da sufuri. Galibi ana adana fili a cikin kwantena masu hana iska don hana iskar oxygen da gurɓatawa. Hakanan yakamata a adana shi daga zafi da wuta, saboda yana da ƙonewa kuma yana iya ƙonewa.
Gabaɗaya, 3,4-difluoronitrobenzene abu ne mai matuƙar amfani kuma mai fa'ida don masana'antar harhada magunguna. Kayayyakinsa na musamman da halayensa sun sa ya zama sinadari mai kima don haɗa nau'ikan magunguna. Yayin da masana'antun harhada magunguna ke ci gaba da haɓakawa da haɓakawa, ana sa ran buƙatun 3,4-difluoronitrobenzene za su tashi, yana mai da shi muhimmin sashi na gaba na ci gaban ƙwayoyi.
