5-Bromo-2-fluoro-4-methyl-pyridine (CAS# 864830-16-0)
| Lambobin haɗari | R22 - Yana cutarwa idan an haɗiye shi R37 / 38 - Haushi ga tsarin numfashi da fata. R41 - Hadarin mummunan lalacewa ga idanu |
| Bayanin Tsaro | S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita. S39 – Sa ido/kariyar fuska. |
| Matsayin Hazard | HAUSHI |
Gabatarwa
Yana da wani kwayoyin halitta tare da tsarin kwayoyin C≡H∞BrFN, wanda ke da zarra na fluorine, rukunin methyl da atom na bromine wanda aka maye gurbinsa akan zoben pyridine.
Hali:
m, mai guba ne kuma mai ban haushi. Yana iya narkewa a cikin kaushi na halitta kamar ethanol da dimethylformamide a dakin da zafin jiki, kuma yana iya haɗa hydrogen tare da wasu masu karɓar haɗin hydrogen (misali, alcohols).
Amfani:
Ana amfani da shi sau da yawa azaman kayan farawa ko tsaka-tsaki a cikin halayen haɗin gwiwar kwayoyin halitta. Ana iya amfani dashi a cikin shirye-shiryen magunguna, magungunan kashe qwari da sauran mahadi. Faɗin aikace-aikacen sa sun haɗa da binciken harhada magunguna, haɗin sinadarai da kimiyyar kayan aiki.
Hanyar Shiri:
Hanyar shirye-shiryen fluorination za a iya samu ta hanyar benzyl bromination da fluorine. Na farko, wani fili na benzyl (4-methylpyridine) yana amsawa tare da benzylidene bromide don samar da fili na bromobenzyl (2-bromo-4-methylpyridine). Ana mayar da wannan fili tare da acid hydrofluoric don samar da samfurin fluorinated daidai (phosphonium).
Bayanin Tsaro:
mai guba ne, yakamata a dauki matakan kariya masu dacewa. Kaucewa tuntuɓar fata, idanu da numfashi yayin aiki. Ya kamata a yi amfani da shi a wuri mai kyau, kuma a sa gilashin kariya masu dacewa, safar hannu da abin rufe fuska. Ajiye nisantar wuta da abubuwan da ke haifar da iskar oxygen, kuma guje wa amsawa da wasu sinadarai. Idan fallasa ko shakar, nemi shawarar likita nan da nan.
