ALPHA-ISO-METHYLIONONE(CAS#127-51-5)
| Alamomin haɗari | Xi - Haushi |
| Lambobin haɗari | 43 - Yana iya haifar da hankali ta hanyar saduwa da fata |
| Bayanin Tsaro | S24/25 - Guji hulɗa da fata da idanu. S36/37 - Sanya tufafin kariya da safar hannu masu dacewa. |
| ID na UN | UN1230 - aji 3 - PG 2 - Methanol, bayani |
| WGK Jamus | 2 |
| Guba | GRAS (FEMA). |
Gabatarwa
gabatar
Cakudar methyl da ethyl isomethyl violet ketone da methyl da ethyl ortho methyl violet ketone.
yanayi
Alpha isomethylprednisolone wani fili ne na kwayoyin halitta. Yana da m crystalline purple. A cikin zafin jiki, yana da ƙamshi na musamman.
Alpha isomethylprednisolone shine ketone mai ƙanshi. An samo shi daga methylation dauki na barasa violet kuma ana kiran shi ketone isomethyl violet. Tsarin kwayoyin halittarsa ya ƙunshi zoben ƙanshi da ƙungiyar ketone.
A cikin zafin jiki, yana da ƙarfi, amma ana iya narkar da shi ta hanyar dumama. Ba shi da narkewa a cikin ruwa, amma yana iya narkewa a cikin wasu kaushi na halitta kamar ethanol da dichloromethane. Yana da kula da haske kuma yana iya shan maganin photolysis a ƙarƙashin hasken ultraviolet.
Dangane da kaddarorin sinadarai, α - isomethylprednisolone wani fili ne mai amsawa. Yana iya fuskantar halayen kamar oxidation, raguwa, ƙari, da canji. Yana amsawa tare da wasu reagents na lantarki don samar da samfuran ƙari. Ana iya yin protonated a gaban acid mai ƙarfi. Hakanan ana iya canza shi zuwa acid ketone ta hanyar halayen iskar shaka.
Hanyar samarwa
Mai zuwa hanya ce ta gama gari don samar da alpha isomethylprednisolone:
Shirye-shiryen kayan farko: Shirya kayan farko, ciki har da Isobutyl ketone da Cyclohexanone. Wadannan mahadi guda biyu sune mahimmancin mahimmanci don haɓakar α - isomethylprednisolone.
Saitin yanayin amsawa: Reacte isodecanone da cyclohexanol a ƙarƙashin yanayin da suka dace. Yanayin halayen gama gari shine don gudanar da martani a ƙarƙashin yanayin acidic, kuma masu haɓaka acid ɗin da aka saba amfani da su sun haɗa da sulfuric acid (H2SO4) da phosphoric acid (H3PO4).
Matakan amsawa: Mix wani adadin isodecanone da cyclohexanol, kuma ƙara mai kara kuzari. Sa'an nan kuma, ana aiwatar da martani a yanayin da ya dace, tare da yawan zafin jiki da ake amfani da shi na 50-70 digiri Celsius. Lokacin amsawa gabaɗaya sa'o'i da yawa ne zuwa dubun awoyi.
Rabuwa da tsarkakewa: Bayan an gama amsawa, samfurin yana tsarkakewa daga cakuda amsa ta hanyar distillation ko wasu hanyoyin rabuwa.
Crystallization da bushewa: Crystallize kuma bushe samfurin da aka tsarkake don samun samfurin isomethylprednisolone na ƙarshe.
