Boc-D-aspartic acid 4-benzyl ester (CAS # 51186-58-4)

Gabatarwa

tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester (Boc-D-aspartic acid 4-benzyl ester) fili ne na kwayoyin halitta. Mai zuwa shine bayanin kaddarorin, amfani, shiri da bayanan aminci na fili:

Hali:

-Bayyana: Farin kristal mai ƙarfi

-Tsarin kwayoyin halitta: C16H21NO6

-Nauyin kwayoyin halitta: 323.34g/mol

- Matsakaicin narkewa: 104-106 ℃

- Solubility: Mai narkewa a cikin abubuwan kaushi na gama gari (kamar ether, methanol, ethanol)

Amfani:

-tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester galibi ana amfani dashi azaman reagent a cikin binciken biochemical, ana amfani dashi don haɗawa ko canza wasu mahaɗan kwayoyin halitta.

Ana amfani da shi sau da yawa a cikin haɗin peptide azaman ƙungiyar karewa don aspartic acid don kare ƙungiyar aiki akan sarkar gefen amino acid kuma aiwatar da amsawar kariya lokacin da ake buƙata.

Hanyar Shiri:

Gabaɗaya, Boc-D-aspartic acid 4-benzyl ester an shirya shi ta hanyar amsawar aspartic acid. Na farko, ana amsa aspartic acid tare da acetyl chloride (AcCl) don ba da aspartic acid acetyl ester. Acetyl kariya aspartate acetyl ester ana amsawa da tert-butoxycarbonyl chloride (Boc-Cl) don ba da tert-butoxycarbonyl-D-aspartate 4-acetyl ester. A ƙarshe, tert-butoxycarbonyl-D-aspartic acid 4-benzyl ester za a iya samu ta hanyar esterification na benzyl barasa da tushe.

Bayanin Tsaro:

- Boc-D-aspartic acid 4-benzyl ester gabaɗaya yana da ƙarancin guba, har yanzu ya zama dole a ɗauki matakan kariya masu dacewa yayin aiki, kamar sa safofin hannu, tabarau da riguna na dakin gwaje-gwaje.

-A guji haɗuwa da fata da shakar ƙura.

-Ajiye shi a busasshiyar wuri mai sanyi, nesa da wuta da abubuwan da ke haifar da iskar oxygen.

-Lokacin sarrafawa da zubarwa, da fatan za a bi matakan tsaro da ƙa'idodi masu dacewa.