BOC-D-ASP(OBZL) -OH (CAS# 92828-64-3)

Gabatarwa

(3R) -4- (benzyloxy) -3- [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (sunan da ba a fi so ba) ((3R) -4- (benzyloxy) -3- [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid) wani fili ne na kwayoyin halitta wanda tsarin kwayoyin halitta shine C16H21NO6.

Haɗin ya samo asali ne na aspartic acid tare da kaddarorin masu zuwa:

-Bayanan shine farin crystalline foda;

-Stable a dakin da zafin jiki, amma zai bazu a babban zafin jiki;

- Mai narkewa a cikin abubuwan da ake amfani da su na yau da kullun kamar methanol, ethanol da dichloromethane.

(3R) -4- (benzyloxy) -3 - [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (sunan da ba a fi so ba) yana da aikace-aikace masu yawa a fagen magani:

-An yi amfani da shi azaman matsakaici don haɗin polypeptides da mahadi tare da ragowar aspartic acid a cikin sunadarai;

-Haka kuma ana iya amfani da shi azaman tsaka-tsaki na roba don magunguna.

A cikin dakin gwaje-gwaje, hanyar shirya (3R) -4- (benzyloxy) -3 - [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (sunan da ba a fi so ba) gabaɗaya ta hanyar amsa ƙungiyar carboxyl na aspartic acid tare da tert-butoxycarbonyl isocyanate, da kuma gabatar da ƙungiyoyin benzyl ester ta hanyar halayen aiki masu dacewa.

Game da bayanin aminci, (3R) -4- (benzyloxy) -3 - [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (sunan da ba a fi so ba) yana da iyakancewar guba da bayanan haɗari, don haka amintaccen aikin sa yakamata ya bi dakin gwaje-gwaje na al'ada. jagororin aminci. Saka kayan kariya da suka dace kamar gilashin, safar hannu da riguna na dakin gwaje-gwaje yayin amfani ko kulawa. A lokaci guda kuma, don guje wa hulɗa da shi tare da oxidants masu ƙarfi da masu ƙonewa.