Boc-D-Glutamic acid 5-benzyl ester (CAS# 35793-73-8)
| Bayanin Tsaro | S22 - Kada ku shaka kura. S24/25 - Guji hulɗa da fata da idanu. |
| WGK Jamus | 3 |
Gabatarwa
Boc-D-Glu (OBzl) -OH (Boc-D-Glu(OBzl) -OH) wani abu ne na halitta. Mai zuwa shine bayanin yanayin sa, amfaninsa, tsarawa da bayanan aminci:
Hali:
-Bayyana: Farin lu'ulu'u foda
-Tsarin kwayoyin halitta: C20H25NO6
-Nauyin Kwayoyin: 379.41
- Matsakaicin narkewa: 118-120 ℃
-Solubility: Mai narkewa a cikin wasu kaushi na halitta, kamar methanol da dichloromethane
Amfani:
- Boc-D-Glu (OBzl) -OH ana amfani da shi a fagen hada magunguna da kuma kira na peptide.
-Ana iya amfani da shi azaman ƙungiyar karewa don peptides don kare ƙungiyar aikin hydroxyl na glutamic acid yayin aikin haɗin gwiwa don hana halayen da ba'a so yayin amsawa.
Hanyar Shiri:
- Boc-D-Glu(OBzl) -OH yawanci ana shirya shi ta hanyar haɗin sinadarai.
-Na farko, tert-butoxycarbonyl (Boc) an shigar da shi a cikin kwayoyin glutamic acid don samar da tert-butoxycarbonyl-D-glutamic acid (Boc-D-Glu).
-Sa'an nan kuma, an shigar da ƙungiyar benzyl (Bzl) a cikin ƙungiyar hydroxyl na glutamic acid don samar da Boc-D-Glu (OBzl) -OH (Boc-D-Glu (OBzl) -OH).
Bayanin Tsaro:
- Boc-D-Glu(OBzl) -OH wani sinadari ne na halitta, wanda zai iya haifar da wani haushi da cutarwa ga jikin mutum.
-Lokacin amfani, kula don kauce wa hulɗa da fata, idanu da kuma numfashi.
-A cikin ayyukan dakin gwaje-gwaje ko samar da masana'antu, yakamata a yi amfani da kayan kariya masu dacewa, kamar safar hannu, gilashin kariya da abin rufe fuska.
-Ajiye daga wuta da oxidizing jamiái, ajiye akwati a rufe, da kuma adana a cikin sanyi da bushe wuri.
Lura cewa wannan cikakken bayani ne kawai kuma baya da alaƙa da takamaiman yanayin gwaji da ayyuka masu aminci. Kafin amfani da wannan fili, ana ba da shawarar tuntuɓar cikakken takaddar bayanan amincin abubuwan sinadarai (MSDS) kuma bi hanyoyin aminci masu dacewa.
