Boc-L-aspartic acid 1-benzyl ester (CAS# 30925-18-9)

Gabatarwa

Boc-Asp-OBzl (Boc-Asp-OBzl) wani fili ne wanda ke da kaddarorin masu zuwa:

1. Bayyanar: Farar crystalline m.

2. Tsarin kwayoyin halitta: C24H27N3O7.

3. Nauyin kwayoyin halitta: 469.49g/mol.

4. Matsayin narkewa: kusan 130-134 ° C.

Ana amfani da Boc-Asp-OBzl sosai a cikin ilimin halittar jiki da sinadarai na halitta, galibi ana amfani da su a cikin haɗin peptides, sunadarai da kwayoyi, tare da amfani masu zuwa:

1. Peptide synthesis: A matsayin wani ɓangare na ƙungiyar masu karewa (Ƙungiyar Kariyar Boc), ana iya kiyaye rukunin amino a cikin aspartic acid amino acid.

2. Bincike na miyagun ƙwayoyi: don haɗin magungunan peptide tare da maganin kumburi, ƙwayar ƙwayar cuta da kuma tsarin tsarin rigakafi.

3. Enzyme dauki: Boc-Asp-OBzl za a iya amfani da enzyme catalyzed dauki substrate.

Hanyar shirya Boc-Asp-OBzl shine kamar haka:

Aspartic acid da benzoyl chloride an ƙera su don samar da tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), wanda daga baya aka amsa da sodium hexoxide don samun matsakaici a cikin nau'in N-hexanoate. A ƙarshe, yana jurewa yanayin benzoylation don samar da Boc-Asp-OBzl.

Kula da waɗannan bayanan aminci lokacin amfani da Boc-Asp-OBzl:

1. Abin da ke tattare da shi zai iya haifar da haushi da rashin lafiyar jikin mutum, kuma ya kamata a guje wa hulɗar fata da idanu kai tsaye.

2. Ya kamata a dauki matakan kariya da suka dace yayin aiki, kamar sanya safar hannu da tabarau.

3. Ka bushe da rufewa yayin ajiya, kuma ka nisanci wuta da oxidant.

4. Lokacin amfani da sarrafa Boc-Asp-OBzl, da fatan za a bi daidaitattun hanyoyin aiki na dakin gwaje-gwaje da aiki mai aminci.

Lura cewa lokacin amfani da Boc-Asp-OBzl ko kowane sinadarai, dole ne ku bi ƙa'idodin aikin aminci masu dacewa, kuma aiwatar da kariya ta sirri da ƙimar haɗari gwargwadon halin da ake ciki.