Boc-L-Glutamic acid 1-benzyl ester (CAS# 30924-93-7)

Gabatarwa

Boc-L-Glutamic acid 1-benzyl ester (Boc-L-Glutamic acid 1-benzyl ester) wani fili ne na kwayoyin halitta tare da tsarin sinadarai na C17H19NO6 da dangin kwayoyin halitta na 337.34. Fari ne mai ƙarfi, mai narkewa a cikin abubuwan kaushi na halitta kamar ethanol, dimethylformamide da chloroform.

Boc-L-Glutamic acid 1-benzyl ester ana amfani dashi da yawa a cikin haɗin haɗin peptide. Ana iya amfani da shi azaman wakili na micellar ko ƙungiyar karewa don kare ƙungiyar amino acid don hana halayen da ba'a so a cikin halayen sinadarai, kuma a lokaci guda yana iya inganta yawan amfanin ƙasa. Bugu da ƙari, ana iya amfani da shi don haɗin magungunan polypeptide da kwayoyin halitta masu alaƙa.

Hanyar shirya Boc-L-Glutamic acid 1-benzyl ester gabaɗaya ita ce gabatar da ƙungiyar kare Boc a cikin rukunin amino ɗin glutamic acid, da aiwatar da amsawar esterification tare da benzyl anhydride ester a wannan matsayi. Ana aiwatar da martani gabaɗaya ƙarƙashin tsaka-tsaki ko yanayi na asali kuma yawanci yana buƙatar takamaiman adadin lokaci don tabbatar da ƙarshen abin da ya faru. Ana iya tsarkake samfurin da aka samu ta hanyar crystallization ko ƙarin matakan tsarkakewa.

Game da bayanin aminci, takamaiman amincin Boc-L-Glutamic acid 1-benzyl ester yana buƙatar ƙarin bincike da kimantawa. Koyaya, a matsayin wakili na sinadarai, yana iya samun ɗan haushi da guba. Dole ne a bi hanyoyin dakin gwaje-gwaje da suka dace yayin saduwa ko amfani, kuma dole ne a ɗauki matakan tsaro da suka dace, gami da sanya kayan kariya na sirri (misali G., safar hannu na lab, gilashin lab, da sauransu). Lokacin amfani ko zubarwa, ya kamata a zubar da sharar da kyau don guje wa gurɓatar muhalli.