CBZ-D-ALLO-ILE-OH (CAS# 55723-45-0)
Gabatarwa
ZD-allo-Ile-OH . DCHA (ZD-allo-Ile-OH · DCHA) sinadari ne na kwayoyin halitta da reagent don kare amino acid. Mai zuwa shine bayanin yanayin sa, amfaninsa, tsarawa da bayanan aminci:
Hali:
-Tsarin sinadarai: C23H31NO5
-Nauyin kwayoyin halitta: 405.50g/mol
-Bayyana: Farin kristal mai ƙarfi
-Mai narkewa: 105-108°C
-Solubility: Mai narkewa a cikin abubuwan kaushi na halitta kamar acetone, ether, dichloromethane, wanda ba a iya narkewa cikin ruwa.
Amfani:
-ZD-allo-Ile-OH . DCHA shine reagent da ake amfani dashi don kare amino acid. Ta hanyar gabatar da ƙungiyar Cbz akan rukunin amino na amino acid, za'a iya hana canjin ƙungiyar amino ta bazata a cikin halayen haɗin sinadarai.
- Ana amfani dashi sau da yawa a cikin ƙwayar peptide, musamman don haɗakar da jerin peptide tare da sifofi ko ayyuka na musamman.
Hanyar Shiri:
- ZD-allo-Ile-OH. Shiri na DCHA yawanci yana farawa daga D-isoleucine, sannan yana amsawa tare da Cbz anhydride don esterification don gabatar da ƙungiyar kare Cbz. A ƙarshe, ana mayar da DCHA (dichloroformic acid) tare da amino acid don samar da gishiri daidai.
Bayanin Tsaro:
-ZD-allo-Ile-OH . DCHA ba ta da guba, amma ya kamata a kula da ita da taka tsantsan. Ka guji haɗuwa da fata da idanu, sa safar hannu masu kariya da tabarau idan ya cancanta.
-Lokacin amfani, ya kamata a bi daidaitattun hanyoyin aiki na dakin gwaje-gwaje kuma a yi amfani da kayan aikin da ya dace.
-Lokacin da ake adanawa, ajiye wurin a bushe, wuri mai sanyi nesa da tushen wuta da buɗe wuta.
