Ethyl 1- (4-methoxyphenyl) -6- (4-aminophenyl) -7-oxo-4 5 6 7-tetrahydro-1H-pyrazolo [3 4-c] pyridine-3-carboxylate (CAS # 503615-07-4) )

Gabatarwa

Mai zuwa shine gabatarwa ga kaddarorin, amfani, hanyoyin shirye-shirye da bayanan aminci na matsakaicin apixaban 3:

inganci:

Apixaban tsaka-tsakin 3 wani fili ne na kwayoyin halitta. Yana da ƙarfi kuma mai narkewa a cikin ƙwayoyin cuta kamar ether da ethyl acetate.

Amfani: An fi amfani da shi don maganin sa barci da kuma maganin ciwo mai tsanani.

Hanya:

Hanyar shiri na apixaban matsakaici 3 za a iya aiwatar da matakai masu zuwa: p-nitrobenzoic acid yana amsawa tare da hypobutylthiourea a cikin kasancewar acetic acid da thionyl chloride don samun N- (p-nitrophenyl) -N- (hypobutylthioylurea) formic acid, sa'an nan kuma, amsa tare da sodium hydroxide a cikin sodium oxide da methanol bayani don samun apixaban. tsakani 3.

Bayanin Tsaro: Ana buƙatar bin tsauraran matakan aiki na aminci lokacin amfani da sarrafa wannan fili. Tuntuɓar kai tsaye ko shakar numfashi na iya haifar da mummunar illa ga lafiyar ɗan adam. Ya kamata a kimanta takamaiman bayanan lafiyar sa da sarrafa su daidai da ƙa'idodi da ƙa'idodi don tabbatar da amintaccen amfani da kulawa. Lokacin yin gwaje-gwajen haɗin gwiwar sinadarai, ya kamata a yi amfani da su a ƙarƙashin yanayin dakin gwaje-gwaje da ya dace kuma a yi amfani da kayan kariya na mutum kamar goggles na sinadarai, safar hannu na kariya, da tufafin kariya.