Fmoc-2-Amino-2-methylpropionic acid (CAS# 94744-50-0)

Gabatarwa

Fmoc-2-aminoisobutyric acid, wanda kuma aka sani da Fmoc-Aib, wani fili ne na kwayoyin halitta. Mai zuwa shine cikakken gabatarwa ga wasu kaddarorin, amfani, hanyoyin shirye-shirye da bayanan aminci na Fmoc-2-aminoisobutyric acid:

inganci:

Fmoc-2-aminoisobutyric acid wani farin crystalline ne mai kauri tare da wari na musamman. Yana da tsayayye a zafin daki kuma ba a iya narkewa a cikin ruwa, amma mai narkewa a cikin kaushi na halitta kamar methanol da methylene chloride.

Amfani:

Fmoc-2-aminoisobutyric acid shine rukuni na kariya da aka saba amfani dashi a cikin haɗin kwayoyin halitta. Ana iya amfani da shi azaman rukuni don kariya ta wucin gadi na ƙungiyoyin amino a cikin polypeptides na roba da sunadaran don hana su daga halayen gefe a cikin halayen sinadarai.

Hanya:

Hanyar shiri na FMOC-2-aminoisobutyric acid shine gabaɗaya ta hanyar haɗin sinadarai. Ana yin wannan yawanci ta hanyar amsawar 2-aminoisobutyric acid tare da Fmoc-OSu (Fmoc-N-hydroxysuccinimidyl) ko Fmoc-OXy (Fmoc-N-hydroxysuccinimidate). Yawanci ana aiwatar da halayen a cikin zafin jiki kuma ana tsarkake shi ta hanyar cire sauran ƙarfi da crystallization.

Bayanin Tsaro:

FMOC-2-aminoisobutyric acid gabaɗaya yana da aminci a ƙarƙashin yanayin amfani na yau da kullun. A matsayin mahadi na halitta, yana iya haifar da wasu haɗari ga lafiyar ɗan adam. Ya kamata a kula don guje wa shakar foda ko mafita yayin guje wa haɗuwa da fata da idanu. Ya kamata a sa safar hannu, tabarau, da abin rufe fuska idan ya cancanta. Idan ana hulɗa da fata ko idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi kulawar likita. Ya kamata a adana shi a cikin bushe, wuri mai sanyi, nesa da wuta da oxidants.