FMOC-Arg(Pbf) -OH (CAS# 154445-77-9)
Hadari da Tsaro
| Alamomin haɗari | Xi - Haushi |
| Lambobin haɗari | 36/37/38 - Hannun idanu, tsarin numfashi da fata. |
| Bayanin Tsaro | S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita. S36 - Sanya tufafin kariya masu dacewa. |
| WGK Jamus | 1 |
| HS Code | 2935 90 90 |
| Matsayin Hazard | HAUSHI |
Gabatarwa
Ƙungiyar kare FMOC ƙungiyar kare amino acid ce da aka saba amfani da ita wacce ke ba da kariya ga rukunin aikin amino na arginine. Mai zuwa shine gabatarwa ga wasu kaddarorin, amfani, hanyoyin shiri, da bayanan aminci na Fmoc-Protective Radical:
inganci:
Ƙungiya mai-kare FMOC ƙungiyar kariya ce mai cirewa wacce ke ba da kariya ga ƙungiyoyin amino amino. Yana iya amsawa tare da rukunin amino a cikin arginine ta hanyar amsawar esterification don samar da Fmoc-arginine ester, don cimma manufar kare rukunin amino. Akwai ƙungiyoyin aromatic akan ƙwayoyin ƙungiyar masu kare Fmoc waɗanda ke ɗaukar hasken UV mai ƙarfi, wanda ke ba da damar cire ƙungiyar kariya ta Fmoc ta hanyar sakawa UV ko hanyoyin sinadarai.
Amfani:
Ana amfani da ƙungiyoyi masu kare FMOC a ko'ina a cikin haɗin peptide da haɓakaccen lokaci mai ƙarfi. Yana iya kare ƙungiyar amino arginine yadda ya kamata don hana halayen gefensa yayin haɗuwa. A cikin kira na peptide, ƙungiyar masu kare Fmoc za a iya cire su ta yanayin alkaline, yana barin haɗin polypeptides ya ci gaba.
Hanya:
Ƙungiyar Fmoc-kariyar za a iya shirya ta hanyar amsawar Fmoc-Cl da arginine. Fmoc-Cl shine reagent mai ƙarfi acidic wanda ke amsawa tare da rukunin amino a cikin arginine don samar da ester Fmoc-arginine. Yawanci ana aiwatar da martanin a cikin ethanol a zazzabi na ɗaki zuwa zafin wanka na kankara.
Bayanin Tsaro:
FMOC-Protective Radicals suna da aminci don amfani a ƙarƙashin yanayin dakin gwaje-gwaje na yau da kullun, amma yakamata a lura da waɗannan abubuwan:
- FMOC-CL wakili ne mai ban haushi da mai guba, ya kamata a kula da shi don kauce wa haɗuwa da fata, shaka ko sha. Yi aiki a wurin da ke da isasshen iska kuma saka kayan kariya masu dacewa.
-Foc-Protective Base yana da kaddarorin ɗaukar ƙarfi na hasken ultraviolet, don haka ya kamata a kula don hana hulɗar kai tsaye da fata da idanu yayin amfani, da nesanta daga tushen haske mai ƙarfi.
- Ana amfani da kariya mai ƙarfi na hydrolysis mai ƙarfi kamar pentafluorophenylcarboxylic acid (TFA) yayin cire ƙungiyoyin kariya na Fmoc, kuma yana da mahimmanci a san cewa tururin TFA na iya haifar da lalacewa, don haka wajibi ne a yi aiki a cikin rijiyar. yanki mai iska.
