fmoc-O-tert-butyl-D-tyrosine (CAS# 118488-18-9)

Fmoc-O-tert-butyl-D-tyrosine amino acid ne mai kariya da aka saba amfani dashi. Mai zuwa shine bayanin yanayin sa, amfaninsa, tsarawa da bayanan aminci:

Hali:
Fmoc-O-tert-butyl-D-tyrosine wani farin kristal ne mai ƙarfi. Yana da kwayoyin halitta tare da tsarin sinadarai C30H31NO7 da nauyin kwayoyin halitta na 521.57g/mol. Filin wani abu ne na tyrosine wanda ƙungiyar amino ɗin ke ɗauke da ƙungiyar kariya ta Fmoc (9-fluorofluorenylformyl) kuma ƙungiyar carboxylic acid an lalata ta da O-tert-butyl.

Amfani:
Fmoc-O-tert-butyl-D-tyrosine yawanci ana amfani dashi azaman amino acid mai kariya a cikin kirar peptide. Ta hanyar haɗa ƙungiyar kariyar Fmoc zuwa rukunin amino, ana iya hana halayen da ba'a so ba yayin haɗakarwa. Ana amfani da shi sosai a cikin m lokaci kira kuma za a iya amfani da su hada polypeptides da sunadarai.

Hanyar Shiri:
Shirye-shiryen Fmoc-O-tert-butyl-D-tyrosine gabaɗaya ana aiwatar da shi ta hanyar haɗin sinadarai. Na farko, an yi maganin tyrosine tare da Fmoc-Cl (9-fluorofluorenylcarbonyl chloride) don samar da Fmoc-O-tyrosine. Cesium tert-butyl bromide kuma an ƙara shi zuwa amsa don tabbatar da ƙungiyar carboxylic acid don samar da Fmoc-O-tert-butyl-D-tyrosine. A ƙarshe, ana samun samfurin mai tsabta ta matakan crystallization, wankewa da bushewa.

Bayanin Tsaro:
Fmoc-O-tert-butyl-D-tyrosine wani abu ne mai tsayayye a ƙarƙashin yanayin al'ada kuma ba shi da bayyanannen canji a cikin zafin jiki. Lokacin amfani, wajibi ne a bi ka'idodin aminci na dakin gwaje-gwaje, sanya kayan kariya masu dacewa, da guje wa haɗuwa da fata da idanu. Lokacin sarrafawa ko adanawa, yakamata a ajiye shi a bushe, wuri mai sanyi kuma daga wuta da abubuwan da ke haifar da iskar oxygen. A lokaci guda kuma, ya kamata a guji tuntuɓar masu ƙarfi masu ƙarfi da acid mai ƙarfi don hana halayen haɗari. Nemi taimakon likita nan da nan idan an sha ko bayyanuwa cikin haɗari zuwa wurin.