Fmoc-L-2-Aminobutyric acid (CAS# 135112-27-5)
Hadari da Tsaro
| Bayanin Tsaro | S22 - Kada ku shaka kura. S24/25 - Guji hulɗa da fata da idanu. |
| WGK Jamus | 3 |
| HS Code | 2924 29 70 |
| Matsayin Hazard | HAUSHI |
Fmoc-L-2-Aminobutyric acid (CAS# 135112-27-5) Gabatarwa
L-2- (fluorenylmethoxycarbonylamino) butyric acid, kuma aka sani da Fmoc-glutamic acid (L-2- (9-fluorenylmethoxycarbonylamino) butyric acid), abu ne na halitta. Mai zuwa shine bayanin wasu kaddarorinsa, amfaninsa, hanyoyinsa da bayanan aminci:
Hali:
-Bayyana: Mara launi ko ɗan ƙaramin rawaya crystalline foda;
-Tsarin kwayoyin halitta: C26H23NO4;
-Nauyin kwayoyin halitta: 413.47g/mol;
-matsayin narkewa: kimanin 166-168 ℃;
-Solubility: Fmoc-glutamic acid yana narkewa a cikin kaushi na halitta kamar dimethylformamide da hydrofluoric acid.
Amfani:
Fmoc-glutamic acid, a matsayin rukunin rukunin karewa, ana amfani da su sau da yawa a cikin haɗin peptide, musamman a cikin haɓakar tsarin peptide barga da haɗin peptides Levenstein (Levenshtein peptide). Ana iya amfani da shi azaman tsaka-tsakin roba na amino acid, ko amfani dashi a cikin ingantaccen lokaci mai ƙarfi, babban aikin ruwa chromatography, da sauransu.
Hanyar Shiri:
Shirye-shiryen Fmoc-glutamic acid gabaɗaya ya haɗa da matakai masu zuwa:
1. A cikin tsarin anhydrous, L-glutamic acid yana amsawa tare da Fmoc-OSu (fluorenylmethoxycarbonyl-chloro anhydride), kuma ana amfani da sodium chloride (NaCl) don inganta halayen don samar da Fmoc-glutamic acid Fmoc-A gishiri.
2. Don gishiri na Fmoc-glutamic acid, an narkar da shi a cikin wani ƙarfi (kamar dimethylformamide) kuma an sanya shi zuwa hanyar tsarkakewa mai dacewa (kamar crystallization) don samun Fmoc-glutamic acid.
Bayanin Tsaro:
Fmoc-glutamic acid gabaɗaya yana da ingantacciyar kwanciyar hankali da ƙarancin guba a ƙarƙashin aiki na yau da kullun. Amma a matsayin mahadi na halitta, har yanzu yana buƙatar kula da matakan aminci masu zuwa:
-A guji shakar kura, tuntuɓar fata da idanu;
-Lokacin aiki, sanya safofin hannu masu kariya, tabarau da tufafi masu kariya waɗanda suka dace da buƙatun aminci;
-Yi aiki a cikin yanayi mai kyau don guje wa fallasa kai tsaye na dogon lokaci;
-Idan za a zubar da shara daga wannan fili, a zubar da shi yadda ya kamata kamar yadda dokokin gida suka tanada.
Hali:
-Bayyana: Mara launi ko ɗan ƙaramin rawaya crystalline foda;
-Tsarin kwayoyin halitta: C26H23NO4;
-Nauyin kwayoyin halitta: 413.47g/mol;
-matsayin narkewa: kimanin 166-168 ℃;
-Solubility: Fmoc-glutamic acid yana narkewa a cikin kaushi na halitta kamar dimethylformamide da hydrofluoric acid.
Amfani:
Fmoc-glutamic acid, a matsayin rukunin rukunin karewa, ana amfani da su sau da yawa a cikin haɗin peptide, musamman a cikin haɓakar tsarin peptide barga da haɗin peptides Levenstein (Levenshtein peptide). Ana iya amfani da shi azaman tsaka-tsakin roba na amino acid, ko amfani dashi a cikin ingantaccen lokaci mai ƙarfi, babban aikin ruwa chromatography, da sauransu.
Hanyar Shiri:
Shirye-shiryen Fmoc-glutamic acid gabaɗaya ya haɗa da matakai masu zuwa:
1. A cikin tsarin anhydrous, L-glutamic acid yana amsawa tare da Fmoc-OSu (fluorenylmethoxycarbonyl-chloro anhydride), kuma ana amfani da sodium chloride (NaCl) don inganta halayen don samar da Fmoc-glutamic acid Fmoc-A gishiri.
2. Don gishiri na Fmoc-glutamic acid, an narkar da shi a cikin wani ƙarfi (kamar dimethylformamide) kuma an sanya shi zuwa hanyar tsarkakewa mai dacewa (kamar crystallization) don samun Fmoc-glutamic acid.
Bayanin Tsaro:
Fmoc-glutamic acid gabaɗaya yana da ingantacciyar kwanciyar hankali da ƙarancin guba a ƙarƙashin aiki na yau da kullun. Amma a matsayin mahadi na halitta, har yanzu yana buƙatar kula da matakan aminci masu zuwa:
-A guji shakar kura, tuntuɓar fata da idanu;
-Lokacin aiki, sanya safofin hannu masu kariya, tabarau da tufafi masu kariya waɗanda suka dace da buƙatun aminci;
-Yi aiki a cikin yanayi mai kyau don guje wa fallasa kai tsaye na dogon lokaci;
-Idan za a zubar da shara daga wannan fili, a zubar da shi yadda ya kamata kamar yadda dokokin gida suka tanada.
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