fmoc-L-4-hydroxyproline (CAS# 88050-17-3)

Gabatarwa

Fmoc-L-hydroxyproline (Fmoc-Hyp-OH) asalin amino acid ne tare da kaddarorin masu zuwa da amfani:

inganci:

- Bayyanar: Fari ko kashe-fari crystalline foda

- Solubility: Mai narkewa a cikin ƙwayoyin halitta kamar DMF, DMSO da methanol

Farashin pKa: 2.76

Amfani:

- Fmoc-Hyp-OH ana amfani dashi galibi don haɓakar peptide da haɓakar peptide a cikin ingantaccen lokaci mai ƙarfi.

- Yana aiki a matsayin wani ɓangare na ƙungiyar kariya don kare ƙungiyoyin aiki na sassan sassan sassan amino acid yayin haɗin lokaci mai ƙarfi don guje wa halayen da ba zato ba tsammani da kiyaye zaɓin zaɓi.

Hanya:

Fmoc-Hyp-OH za a iya shirya ta hanyar amsawa Fmoc-amino acid tare da L-hydroxyproline a cikin mai dacewa. Yanayin amsawa yawanci sun haɗa da yanayin zafin da ya dace da ingantaccen tushe mai haɓakawa, kamar N, N-dimethylpyrrolidone (DMAP). Samfurin da aka samo ana tsarkake shi ta matakai kamar hazo, wanki, da bushewa.

Bayanin Tsaro:

- FMOC-HYP-OH fili ne na halitta kuma yakamata a sarrafa shi daidai da ka'idojin aminci na dakin gwaje-gwaje.

- Ana iya shakar kurar ta hadu da fata, don haka a kula don gujewa shakar iska ko tuntubar juna.

- A yayin aikin, yakamata a sanya kayan kariya masu dacewa kamar safofin hannu na dakin gwaje-gwaje, kariyar ido, tufafin kariya, da sauransu.

- Ya kamata a adana shi sosai a cikin busasshen wuri mai sanyi, nesa da wuta da abubuwa masu ƙonewa.