Fmoc-L-Glutamic acid 1-tert-butyl ester (CAS# 84793-07-7)

Gabatarwa

Fluorene methoxycarbonyl-L-glutamate-1-tert-butyl ester, wanda kuma aka sani da Fmoc-L-glutamic acid-1-tert-butyl ester, wani fili ne na kwayoyin halitta wanda aka saba amfani dashi a cikin kira na peptide da kuma hadaddiyar lokaci-lokaci a cikin haɗin kwayoyin halitta.

inganci:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl wani m tare da fari zuwa rawaya lu'ulu'u. Yana da low solubility a cikin ruwa amma mai kyau solubility a Organic kaushi kamar dimethyl sulfoxide ko methanol.

Amfani:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl shine amino acid da aka saba amfani dashi a cikin haɗin peptide. Ana iya amfani da shi don kare ƙungiyar ta hanyar amsawa, don haka an fallasa shi a cikin haɗin gwiwa da kuma ƙara ƙarar sarkar peptide. Wannan fili ya dace musamman don haɗakar lokaci mai ƙarfi, inda sarƙoƙin peptide ke haɗa su zuwa amino acid masu kariya akan rassan guduro.

Hanya:

Shirye-shiryen fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl yawanci ana samun su ta hanyar haɗin sinadarai. Fluorene methanol an fara haɗa shi cikin fluorene carboxyl chloride ta hanyar halayen sinadarai, sannan ya amsa da L-glutamic acid don samar da fluorene methoxycarbonyl-L-glutamic acid, kuma a ƙarshe ya amsa da tert-butanol don samar da samfurin ƙarshe.

Bayanin Tsaro:

Fluorene methoxycarbonyl-L-glutamic acid-1-tert-butyl ana ɗauka gabaɗaya baya da wani takamaiman guba ga ɗan adam a ƙarƙashin yanayin gwaji na yau da kullun. Ana buƙatar bin ƙa'idodin aminci na dakin gwaje-gwaje masu dacewa yayin gudanarwa, gami da sa safofin hannu na kariya da tabarau, da aiki cikin yanayi mai kyau.