Fmoc-L-homophenylalanine (CAS# 132684-59-4)
Hadari da Tsaro
| Alamomin haɗari | Xi - Haushi |
| Lambobin haɗari | 36/37/38 - Hannun idanu, tsarin numfashi da fata. |
| Bayanin Tsaro | S22 - Kada ku shaka kura. S24/25 - Guji hulɗa da fata da idanu. S44 - S35 - Dole ne a zubar da wannan abu da kwandonsa a hanya mai aminci. S28 - Bayan haɗuwa da fata, wanke nan da nan da sabulu-suds mai yawa. S7 – Rike akwati a rufe sosai. S4 - Nisantar wuraren zama. |
| WGK Jamus | 3 |
| HS Code | 2924 29 70 |
| Matsayin Hazard | HAUSHI |
Gabatarwa
2. Solubility: Mai narkewa a cikin kwayoyin halitta irin su dimethyl sulfoxide (DMSO) da ethyl acetate (EtOAc), wanda ba a iya narkewa a cikin ruwa.
3. dabarar kwayoyin: C32H29NO4.
4. Nauyin kwayoyin: 495.58.
Babban amfani da Fmoc-L-homophenylalanine shine azaman ƙungiyar karewa a cikin haɗin peptide. Fmoc taƙaitaccen furoyl ne da abubuwan da suka samo asali, wanda zai iya kare rukunin amino a cikin amino acid. Lokacin da ake son haɗa sarkar peptide, ana iya samar da rukunin amino don amsawa ta hanyar cire ƙungiyar kare Fmoc. Saboda haka, Fmoc-L-homophenylalanine yana taka muhimmiyar rawa a cikin shirye-shiryen magungunan peptide da kwayoyin halitta masu alaƙa.
Hanyar shirye-shiryen Fmoc-L-homophenylalanine yana da rikitarwa kuma ya haɗa da amsawar kira mai yawa. Hanyar shiri na yau da kullun ita ce ta hanyar haɗakar da phenylalanine mai kariya ta Fmoc tare da sauran reagents, irin su azurfa azide formate (AgNO2), biye da maganin trifluoroacetic acid don ba Fmoc-L-homophenylalanine.
Ya kamata a lura da bayanan aminci masu zuwa yayin amfani da Fmoc-L-homophenylalanine:
1. Nisantar saduwa da fata, idanu da maƙarƙashiya kai tsaye, domin yana iya cutar da jikin ɗan adam.
2. Ajiye ya kamata ya guje wa hulɗa tare da oxidants mai ƙarfi ko acid mai ƙarfi don hana halayen haɗari.
3. Yi amfani da kayan kariya masu dacewa kamar safar hannu, gilashin kariya da riguna na dakin gwaje-gwaje yayin amfani da kulawa.
4. Dole ne a gudanar da duk ayyukan a ƙarƙashin yanayin dakin gwaje-gwaje masu isasshen iska.
A taƙaice, Fmoc-L-homophenylalanine ƙungiyar kare amino acid ce da aka saba amfani da ita wajen haɗin peptide kuma tana da aikace-aikace da yawa. Lokacin amfani da kuma kula da fili, ya zama dole a kula da kulawa mai aminci da adanawa.
