N-Cbz-D-Tryptophan (CAS# 2279-15-4)

Gabatarwa

N(^ a)-Benzyloxycarbonyl-D-tryptophan(N(^ a)-Benzyloxycarbonyl-D-tryptophan) wani sinadari ne, kuma aka sani da CBZ-D-Trp. Mai zuwa shine bayanin yanayin sa, amfaninsa, tsarawa da bayanan aminci:

Hali:

N(^ a)-Benzyloxycarbonyl-D-tryptophan fari ne zuwa rawaya mai kauri. Yana da ingantacciyar kwanciyar hankali a cikin zafin jiki kuma ana iya adana shi na dogon lokaci a ƙarƙashin yanayin rashin ruwa. Ba shi da narkewa a cikin ruwa, amma yana narkewa a cikin wasu kaushi na halitta kamar methanol da dimethyl sulfoxide.

Amfani:

N(^ a)-Benzyloxycarbonyl-D-tryptophan ana yawan amfani da su azaman ƙungiyoyin karewa a cikin haɗaɗɗun kwayoyin halitta, musamman a cikin haɗin peptide sunadarai. Babban amfani da shi shine azaman tushen amino acid don haɗa takamaiman kayayyaki a cikin polypeptide ko sarƙoƙin furotin. Zai iya taka muhimmiyar rawa wajen hada sabbin kwayoyi ta wannan hanya.

Hanya:

Shirye-shiryen N (^ a) -Benzyloxycarbonyl-D-tryptophan yawanci ana yin su ta hanyar haɗakar sinadarai. Da farko, ana amsa barasa na benzyl da carbon dioxide don samar da benzyloxycarboxylic acid, sa'an nan kuma amino acid tryptophan da benzyloxycarboxylic acid suna esterified don samun samfurin CBZ-D-Trp. Halin yana buƙatar taimako na wasu masu kara kuzari da kaushi.

Bayanin Tsaro:

N(^ a)-Benzyloxycarbonyl-D-tryptophan yana da iyakataccen bayanin aminci, amma bisa ga bayanan da ake samu, galibi ana ɗaukarsa mai guba. Bayyanawa na dogon lokaci ko wuce gona da iri na iya samun mummunan tasirin lafiya. Don haka, dole ne a ɗauki matakan tsaro da suka dace yayin amfani, adanawa da sarrafa wannan fili, gami da sanya kayan kariya masu dacewa da kulawa a cikin yanayi mai kyau. A lokaci guda, wajibi ne a bi hanyoyin da suka dace na aikin aminci da hanyoyin zubar da su.

Lura cewa wannan labarin bayyani ne kawai na mahallin da ake tambaya, kuma takamaiman aikace-aikacen da ƙimar haɗari yakamata a gudanar da shi a cikin takamaiman yanayin dakin gwaje-gwaje. Kafin amfani da kowane sinadari, da fatan za a tabbatar da yin nazarin bayanan da suka dace daki-daki kuma tuntuɓi ƙwararru a gaba.