N-Cbz-L-Leucine (CAS# 2018-66-8)
Hadari da Tsaro
| Alamomin haɗari | Xn - cutarwa |
| Lambobin haɗari | R10 - Flammable R20/22 - Yana cutar da numfashi kuma idan an haɗiye shi. R37 / 38 - Haushi ga tsarin numfashi da fata. R40 - Shaida mai iyaka na tasirin cutar sankara R41 - Hadarin mummunan lalacewa ga idanu R36 / 37/38 - Haushi ga idanu, tsarin numfashi da fata. R20/21/22 - Cutarwa ta hanyar shakarwa, a cikin hulɗa da fata kuma idan an haɗiye shi. R67 - Tururi na iya haifar da bacci da dizziness R63 - Haɗarin cutarwa ga ɗan da ba a haifa ba R19 - Zai iya samar da peroxides masu fashewa |
| Bayanin Tsaro | S16 - Ka nisantar da tushen wuta. S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita. S36 / 37/39 - Sanya tufafin kariya masu dacewa, safar hannu da kariya / ido / fuska. S45 - Idan akwai haɗari ko kuma idan kun ji rashin lafiya, nemi shawarar likita nan da nan (nuna alamar a duk lokacin da zai yiwu.) S36 - Sanya tufafin kariya masu dacewa. S36/37 - Sanya tufafin kariya da safar hannu masu dacewa. S60 - Wannan abu da kwandonsa dole ne a zubar da shi azaman shara mai haɗari. |
| ID na UN | UN 1993 3/PG 3 |
| WGK Jamus | 3 |
| RTECS | OH2921000 |
| HS Code | 29242990 |
N-Cbz-L-Leucine (CAS# 2018-66-8) gabatarwa
Cbz-L-leucine, cikakken sunan Boc-L-leucine (Boc yana nufin ƙungiyar kare dibutoxycarbonyl), asalin amino acid ne. Mai zuwa shine gabatarwa ga yanayinsa, amfaninsa, hanyoyin masana'anta da bayanan aminci:
inganci:
- Bayyanar: Farar crystalline m
- Mai narkewa: Mai narkewa a cikin ethanol, dimethylformamide (DMF) da dichloromethane
Amfani:
- CBZ-L-Leucine ƙungiyar kare amino acid ce da aka saba amfani da ita wacce ke ba da kariya ga rukunin hydroxyl na leucine yayin haɗin peptides don hana shi amsawa da sauran masu amsawa. A cikin haɗin peptide inda ake buƙatar gabatar da ragowar leucine da yawa, Cbz-L-leucine za a iya amfani da shi don kare ƙungiyar hydroxyl na leucine don matakai na gaba.
- Leucine wani muhimmin amino acid ne wanda ke taka muhimmiyar rawa a tsarin gina jiki da aiki.
Hanya:
- Ana samun shirye-shiryen Cbz-L-leucine gaba ɗaya ta hanyar amsawar leucine tare da Boc-OSu (Boc-N-nitrocarbonyl-L-leucine). A cikin martanin, Boc-OSu yana aiki azaman mai gabatarwa na ƙungiyar karewa kuma yana jure yanayin esterification tare da leucine don samar da Cbz-L-leucine.
Bayanin Tsaro:
- Cbz-L-leucine sinadari ne kuma yakamata a adana shi yadda ya kamata daga kunnawa da oxidants.
- Yayin amfani da shi, a guji shakar ƙurarsa ko cudanya da fata da idanu.
- Bi matakan aminci masu dacewa lokacin sarrafawa da adanawa, kuma sanya kayan kariya masu dacewa kamar safofin hannu na lab da kariyan ido.
