NN-Bis 9-fluorenylmethyloxycarbonyl-L-histidine CAS 98929-98-7

Bayanin Tsaro	S22 - Kada ku shaka kura. S24/25 - Guji hulɗa da fata da idanu.
HS Code	29242990

N (alpha), N (im) -di-fmoc-L-histidine (N (alpha), N (im) -di-fmoc-L-histidine) wani fili ne da aka samu ta hanyar sinadarai na 9-fluorenecinol da L. - histidine. Tsarin sinadaransa shine C42H38N4O8 kuma dangin kwayoyin halittarsa ​​shine 722.78g/mol.N (alpha), N(im) -di-fmoc-L-histidine wani fili ne wanda ke kare amino acid kuma ana amfani dashi sosai a cikin hadawar kwayoyin halitta da halayen biochemical. . An fi amfani da shi don daidaita tsarin gina jiki da aiki, da kuma fadadawa da haɓaka aikace-aikacen sarƙoƙi na polypeptide. Ana amfani da wannan fili sosai a cikin ingantattun dabarun haɗin lokaci don gyaggyarawa N-terminus da ragowar histidine na peptide da ƙwayoyin furotin.

Hanyar shirya N(alpha),N(im) -di-fmoc-L-histidine yawanci ya ƙunshi matakai uku. Na farko, ethylene glycol dimethyl ether da diazotoluene an mayar da su a karkashin catalysis na cuprous chloride don hada 9-fluorenmethanol. Sa'an nan, 9-fluorenecinol da L-histidine suna amsawa a ƙarƙashin yanayin acidic don samun N (alpha), N (im) -di-fmoc-L-histidine. A ƙarshe, ana samun samfurin mai tsabta ta hanyar crystallization da matakan tsarkakewa.

Game da bayanin aminci, N (alpha), N (im)-Babu yawancin rahotannin bincike masu dacewa akan takamaiman amincin di-fmoc-L-histidine, don haka ana buƙatar taka tsantsan. Lokacin amfani da shi a dakin gwaje-gwaje, yakamata a ɗauki matakan tsaro da suka dace, gami da sanya kayan kariya masu dacewa, kamar safofin hannu na dakin gwaje-gwaje da tabarau, da guje wa haɗuwa da fata da idanu. A lokaci guda kuma, ya kamata a adana shi a cikin busassun busassun, iska da kuma rufaffiyar akwati, nesa da wuta da kayan wuta. Don cikakkun bayanan aminci, ana ba da shawarar tuntuɓar wallafe-wallafen da suka dace ko tuntuɓar ƙwararru.