(S)-(-)-1 2-Diaminopropane dihydrochloride (CAS# 19777-66-3)
Hadari da Tsaro
| Lambobin haɗari | R36 / 37/38 - Haushi ga idanu, tsarin numfashi da fata. R23/24/25 - Mai guba ta numfashi, a cikin hulɗa da fata kuma idan an haɗiye shi. |
| Bayanin Tsaro | S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita. S36 - Sanya tufafin kariya masu dacewa. S45 - Idan akwai haɗari ko kuma idan kun ji rashin lafiya, nemi shawarar likita nan da nan (nuna alamar a duk lokacin da zai yiwu.) S36 / 37/39 - Sanya tufafin kariya masu dacewa, safar hannu da kariya / ido / fuska. |
| WGK Jamus | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29212900 |
(S)-(-)-1 2-Diaminopropane dihydrochloride (CAS# 19777-66-3) Bayani
| Dubawa | (S) - (-) diaminopropane dihydrochloride za a iya amfani da shi azaman tsaka-tsakin haɗin magunguna, irin su shirye-shiryen Dexrazoxane, shine dextrorotatory enantiomer na magungunan antitumor razoxane. Don magungunan kariyar zuciya, na asibiti don Rigakafin magungunan anthracycline na maganin ciwon daji da ke haifar da gubar zuciya da cutar sankarar bargo a cikin yara saboda chemotherapy da lalacewa ta hanyar zuciya, sau da yawa a matsayin adjuvant a maganin ciwon daji. |
| Amfani | (S) - (-) diaminopropane Dihydrochloride shine tsaka-tsakin kwayoyin halitta, ana iya shirya shi ta hanyar amsawa D- (-) tartaric acid da propylenediamine. An yi amfani da diamine a cikin haɗin haɗin chiral imidazoline |
| shiri | shirye-shiryen (S) - (-) diaminopropane dihydrochloride: ƙara 30.0gD- (-) tartaric acid da 8.0 ml ruwa da g (±) -1, 2-propanediamine a cikin flask dauki, motsawa don narke, sanyi, ƙara. Dropwise, an ɗaga zafin jiki zuwa reflux na sa'o'i 2 tare da motsawa. An dakatar da motsa jiki, kuma an ɗaga zafin jiki zuwa 80 ° C. Don 1 hour. Sa'an nan kuma, an rage zafin jiki a hankali kuma a hankali an sauke shi zuwa zafin jiki, tsotsa, da kuma bushewa don samun 16.1g na (S) -1, 2-propanediamine ditartrate. Add 16.1g na (S) -1, 2-propanediamine ditartrate da na ruwa a cikin flask dauki, narke da dumama, sa'an nan kuma ƙara wani bayani na 7.43g na potassium chloride da 20ml na ruwa, da cakuda da aka zuga a 70 °c. na 2 hours. Bayan sanyaya, an bar firiji ya tsaya don crystallization. An tace tacewa tare da tsotsa kuma an distilled zuwa bushewa a ƙarƙashin rage matsa lamba don ba da 84% G na rawaya mai ƙarfi (3), samar da 4.02, [α] 20D = - ° (C = 1%, H2O). |
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