(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER (CAS# 91229-91-3)

Gabatarwa

di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate wani fili ne wanda tsarin sinadarai shine C14H23NO6. Mai zuwa shine bayanin kaddarorin, amfani, shiri da bayanan aminci na fili:

Hali:

-Bayyana: di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate mara launi zuwa farin crystalline m.

-Solubility: Yana narkewa a cikin kaushi na halitta kamar ethanol, methanol da dimethyl sulfoxide.

-Ma'anar narkewa: Filin yana narkewa a kusan 104-105 ° C.

Amfani:

di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate shine abin da aka saba amfani da shi na amino acid wanda aka saba amfani dashi azaman reagent a cikin haɓakar kwayoyin halitta. Ana iya amfani da shi don haɗa abubuwa masu aiki na halitta, kamar kwayoyi da kayan polymer.

Hanya:

Shirye-shiryen di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate yawanci ana aiwatar da su ta hanyoyi masu zuwa:

1. Narke pyroglutamic acid tert-butyl ester a bushe dimethyl sulfoxide.

2. An ƙara adadin da ya dace na N, N'-dihydroxyethyl isopropanamide kuma an sanyaya cakuda cakuda zuwa ƙasa 0 ° C.

3. Ƙara di-tert-butyl carbonate sannu a hankali yayin da ke riƙe da zafin jiki na cakuda da ke ƙasa 0 ° C.

4. Bayan kammala aikin, an ƙara cakudaccen abu a cikin ruwa don samar da hazo mai ƙarfi na di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate.

5. An samo samfurin ƙarshe ta hanyar matakan crystallization, tacewa da bushewa.

Bayanin Tsaro:

di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate ya kamata a yi amfani da shi kuma a kula da shi daidai da ayyuka masu aminci don kauce wa fallasa fata, idanu da shakarwa. Bugu da ƙari, ya kamata a adana shi a cikin bushe, wuri mai sanyi kuma daga wuta da oxidants. Don takamaiman bayanin aminci, koma zuwa Takardar bayanan Tsaron Chemical (MSDS) ko bayanan da suka dace da mai siyarwa ya bayar.